Purification, Characterization, and Antiproliferative Activity of a Single?Chain Lectin from Vicia palaestina (Fabaceae) Seeds
نویسندگان
چکیده
Vicia palaestina Boiss. is an annual herb that grows in dry areas of eastern Mediterranean countries. It belongs to section Cracca subgenus Vicilla, which characterized by having a high content the non-protein amino acid canavanine. The seeds from some these vetches are also rich lectins. purification and characterization single-chain lectin V. described here. This was most abundant protein albumin extracts. has affinity for glycoconjugate N-acetylgalactosamine inhibits proliferation cancerous Caco-2 THP-1 cell lines. In addition their nutritional value, represent source lectins with health promoting pharmacological potential because antiproliferative activity.
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ژورنال
عنوان ژورنال: Chemistry & Biodiversity
سال: 2021
ISSN: ['1612-1872', '1612-1880']
DOI: https://doi.org/10.1002/cbdv.202000827